cd40 ligand การใช้

• More specifically, Lentiviruses attach to the CD40 ligand glycoproteins on the surface of T-lymphocyte cells.
• CD40 ligand is primarily expressed on activated CD4 + T lymphocytes but is also found in a soluble form.
• SAg activation in T-cells leads to production of CD40 ligand which activates isotype switching in B cells to IgG and IgM and IgE.
• Despite the setbacks, IDEC Pharmaceuticals of San Diego is now testing its own antibody against the same target _ known as CD40 ligand _ in psoriasis and other autoimmune diseases.
• TLR10's mechanism of action is not yet known but activation of the receptor has been shown to suppress NF-kB, MAP kinase and Akt signaling events stimulated by TLR and CD40 ligands.
• Appears in the blood a $ m-m } lt of inflammation or infection anywhere in the body . $-- _ ] mmcental growth factor, or PlGF . A protein also involved iomoommmmation . _ CD40 Ligand.